On-demand, the H100 rents for $4.00/hr and the MI325X for $3.18/hr — the MI325X is ~26% cheaper per hour, averaged across cloud providers.
| H100 | MI325X | |
|---|---|---|
| On-demand /hr | $4.00 | $3.18 |
| Spot /hr | $1.71 | $2.00 |
| Reserved /hr | $3.49 | $2.03 |
| Per month (on-demand) | $2,920 | $2,321 |
| H100 | MI325X | |
|---|---|---|
| Vendor | NVIDIA | AMD |
| Architecture | Hopper | CDNA 3 |
| Memory | 80 GB HBM3 | 256 GB HBM3e |
| Memory bandwidth | 3.35 TB/s | 6 TB/s |
| Launched | 2022 | 2025 |
On-demand, the H100 averages $4.00/hr vs the MI325X at $3.18/hr — the MI325X is about 26% cheaper per hour. Spot rates are $1.71/hr vs $2.00/hr.
H100 costs more per hour but offers 80 GB HBM3 memory and newer architecture — for large-model training the higher hourly rate often yields a lower cost-per-job. For memory-bound inference or budget runs, the MI325X is usually the better value.
At on-demand rates that's about $2,920/mo for the H100 and $2,321/mo for the MI325X (730 hours).
See full pricing & history: H100 price · MI325X price · all GPUs.
Cross-provider averages from public cloud GPU listings. Informational only.